DIFFERENCE BETWEEN PERIODONTAL PATHOGENS IN STAGE III AND IV PERIODONTITIS PATIENTS WITH CHRONIC KIDNEY DISEASE: A PILOT STUDY

Abstract

This study aimed to investigate difference between periodontal pathogens stage III and IV periodontitis patients with chronic kidney disease (CKD) as a pilot study. 21 participants were included and divided into 2 groups (Stage III periodontitis n=12, Stage IV periodontitis n=9) then periodontal, renal parameters were measured. Saliva, supragingival plaque and subgingival plaque were collected and measured by real-time PCR. The results showed that P. gingivalis from supragingival plaque of stage III and IV patient with CKD was significantly different at P value < 0.05. The richness of oral microbiota is different in stages of periodontitis which may also increase the severity of CKD.