EFFECTS OF 5% CENTELLA ASIATICA EXTRACT CREAM FOR SKIN WHITENING

Abstract

Fair skin has traditionally been associated with beauty, prestige, and social advantage in many Asian cultures, leading to a strong demand for skin-lightening products. Melanin synthesis, regulated primarily by the enzyme tyrosinase, plays a critical role in determining skin pigmentation, and inhibiting this pathway forms the basis of many whitening agents. Conventional treatments include hydroquinone, arbutin, kojic acid, niacinamide, and ascorbic acid, alongside physical methods such as lasers, chemical peels, and cryotherapy. However, concerns regarding safety and toxicity have shifted attention toward herbal alternatives. Centella asiatica (Gotu Kola), widely recognized for its anti-inflammatory, antioxidant, and skin-hydrating properties, has recently been investigated for its potential tyrosinase-inhibiting and skin-whitening effects. Literature suggests that Centella asiatica, when combined with other active compounds, demonstrates tyrosinase-inhibiting activity and skin-lightening potential. However, evidence on its independent efficacy remains limited. This study aims to evaluate the whitening effect and user satisfaction of a topical Centella asiatica cream, thereby contributing to the evidence base for safe and affordable herbal agents in cosmetic dermatology.