A COMPARATIVE STUDY OF THE EFFICACY OF 4% WHITE RADISH ROOT EXTRACT CREAM VERSUS 2% ALPHA ARBUTIN CREAM IN FACIAL WHITENING

Abstract

This study aims to evaluate the effectiveness of radish root extract in facial whitening and to compare its results with the well-established whitening agent, 2% alpha-arbutin. The primary objective is to examine how a 4% radish root extract cream performs in terms of facial skin whitening, in comparison to a 2% alpha-arbutin cream, which is widely used in the treatment of hyperpigmentation. The study followed a parallel group design, with the two different creams being applied and observed simultaneously. During the 12-week period, the effectiveness of the creams was assessed using advanced skin analysis technologies, including the Mexameter® MX18 and VISIA® systems, to measure any changes in pigmentation and skin tone. A total of 24 volunteers, consisting of both male and female participants aged between 20 and 50 years, with Fitzpatrick skin types II to V, were included in the study. The participants were instructed to apply either a cream containing 4% radish root extract or a cream containing 2% alpha-arbutin to their faces twice daily for a period of 12 weeks. The results demonstrated that the 4% radish root extract cream significantly reduced pigmentation, with no reported side effects, indicating its safety and effectiveness. Radish root extract, known for inhibiting the tyrosinase enzyme and its antioxidant properties, presents a promising natural alternative to traditional whitening agents like alpha-arbutin. Additionally, its low cost and ease of cultivation in Thailand support its potential as a viable, affordable option for skin whitening.