DENTIN REMINERALIZATION OF FLUORIDE TOOTHPASTE AND NANO-HYDROXYAPATITE TOOTHPASTE: A PILOT STUDY

Abstract

This study compares the remineralization of dentin by dividing subjects into three groups: a control group, a toothpaste containing 1,000 ppm fluoride, and a toothpaste containing 10% nano-hydroxyapatite. Surface microhardness was measured using a Vickers microhardness tester before and after simulating an oral pH cycling process for 14 days. The study found that the microhardness of the fluoride toothpaste showed the best results, followed by the nano-hydroxyapatite toothpaste, and the control group, respectively. When comparing the percentage changes in surface microhardness between the three groups using One-way ANOVA, significant differences were observed in all group (p < 0.001). Pairwise comparisons using Turkey’s test revealed statistically significant differences across all three pairs (p < 0.05). Therefore, it can be concluded that the fluoride toothpaste is more dentin remineralization than nano-hydroxyapatite toothpaste.