THE EFFICACY OF 2% Andrographis paniculata EXTRACT CREAM IN REDUCING PERIORBITAL WRINKLES AND HYPERPIGMENTATION

Abstract

This study evaluated the efficacy of 2% Andrographis paniculata extract eye cream in reducing periorbital wrinkles and periorbital hyperpigmentation. Using a doubled blinded split face randomized controlled trial, the researcher analyzed improvements in skin elasticity, melanin index, and wrinkle score. Over a 12-week period, 19 participants aged 25 to 50 years applied the cream twice daily. Results showed a statistically significant improvement in wrinkle and hyperpigmentation scores compared to the placebo group, with no side effects reported. These findings suggest that Andrographis paniculata extract can be an effective natural treatment for periorbital wrinkles and hyperpigmentation concerns.