PRELIMINARY STUDY ON GREEN SYNTHESIS OF CHITOSAN MAGNETIC NANOPARTICLES COATED CURCUMIN AS NANOPARTICLES

Abstract

This research is a preliminary study on the green synthesis of magnetic nanoparticles coated with chitosan and curcumin (Fe3O4 / CS @Cur) for use in a nano-level drug delivery system. Environmentally friendly chemicals were employed in the synthesis process to reduce the use of hazardous substances. Chitosan was utilized to enhance biocompatibility, while curcumin, with its anti-inflammatory and anticancer properties, was coated to improve drug delivery efficiency. The synthesized nanoparticles appeared as fine black powder. FTIR analysis revealed the formation of chemical bonds between Fe3O4, chitosan, and curcumin confirming the success of the preliminary synthesis. These results represent an important step towards the development of nanoparticles for an efficient drug delivery system in the future.