ACCESSMENT OF NATURAL PRODUCTS ON FIBROBLAST CELL VIABILITY

Abstract

The objective of this research was to evaluate the effects of various natural extracts including Cissus quadrangularis Linn., Artocarpus lakoocha Roxb., Curcuma aeruginosa Roxb., and Cannabis sativa L. on fibroblsts cells viability. The MTT assay was used to assess the vitality of mouse fibroblast cells after being tested with natural extract for 24 h at various concentrations. Results showed that the extracts from Cissus quadrangularis Linn., Artocarpus lakoocha Roxb., Curcuma aeruginosa Roxb., and Cannabis sativa L. revealed different effects on the viability of fibroblast cells at varying concentrations. However, the trend of fibroblast cell viability relative to the concentration levels of each extract showed a similar pattern. Higher concentrations of the extracts tended to be toxic to the fibroblast cells, while lower concentrations of the extracts promoted the growth of fibroblast cells.